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Level 9: ATACseq & The Genome

Computational Genomics Lab

Intro to Computational Genomics Lab : Level 9

At this level, learners understand how chromatin accessibility relates to genome structure and function. They explore the biological implications of ATAC-seq data.

Download Mouse Genome Annotation HERE

Download ATACseq Pipeline output files HERE

Click here to watch the full video

We are all done !! Now let's KNIT our ATACseq Analyses. Let's compile our results!

Watch YouTube Video Now

Go to Level 10 !

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What Former Students Are Saying

Dr. Rinn is not only an incredible scientist but a great instructor, and I have learned a lot from his class.

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100000000000000/10 class! I never thought I would understand coding at all, but now I do!

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Love professor Rinn and his class, really enjoyed the flow of the class and I felt like the format really worked well.

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This class was awesome. There was a huge emphasis on real world experience, and I really liked this aspect of the course. I wish there were a bit more guidance on the projects, but other than that I don't have any real complaints. Using a supercomputer was awesome and even helped me market myself for a job. Thank you for a great semester and I will be telling everyone to take this class!

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Level 9: ATACseq & The Genome

What do our ATACseq Peak Files look like? Let's Load them (Granges) and see!

Do peaks overlap across samples? Let's find out, using find overlaps function

Where do our ATACseq Peaks Live? Let's learn to map Peaks to Genome Features

Are ATACseq peaks different between samples? Do our peaks change due to Dox?

Can we use DESEQ to find which peaks change upon exposure to dox? Yes we can!

We are all done !! Now let's KNIT our ATACseq Analyses. Let's compile our results!