Genetic Models Of Lncrna

Genetic Models Of Lncrna

“The laws of genetics have never depended upon knowing what the genes are chemically and would hold true even if they were made of green cheese” – Ed Lewis The ultimate demonstration of the functional contribution of a lncRNA is through genetic testing. If DNA containing a lncRNA is removed and the organism is affected, then it must be important, no matter its molecular mode of action. We further use “genetic rescue” models to identify those lncRNAs that have RNA based physiological functions. To date our laboratory has examined over 40 unique genetic modifications of lncRNAs — however we are now out of this business — for now.